贾娴(沈阳药科大学制药工程学院博士研究生导师)简介

2016-04-26 16:56:45来源:沈阳药科大学研究生院
新东方在线考博为大家整理了沈阳药科大学博士生导师信息,供参考联系,祝大家进入理想院校读博。
导师简介
导师姓名 贾娴 性别 出生年月 1968.10 导师类别 博导
研究方向 不对称合成\新药研究
024-23986456 职称/院士 教授
E-mail jiaxian206@163.com 导师学位 博士
学院(工作单位) 制药工程学院
信箱(地址) 46号信箱
贾娴,制药工程学院药物化学教研室教授,博士生导师。

教育背景
1986-1991:沈阳药科大学英语药学专业(五年制)本科生
1991-1994:沈阳药科大学药物化学专业硕士研究生
2000-2003:沈阳药科大学药物化学博士研究生
2001-2003:香港理工大学手性开放重点实验室访问学者

获奖情况
辽宁省百千万工程人才百人层次人选(2011年)
Tetrahedron最佳引用论文奖(Elsevier 公司颁发, 2008年)
辽宁省高等学校优秀青年骨干教师(2006年)
辽宁省自然科学学术成果一等奖(2011年)
辽宁省自然科学学术成果二等奖(2006年)
辽宁省自然科学学术成果三等奖(2005年)
中国药学会第七届全国青年药学工作者最新科研成果二等奖(2004年)
沈阳药科大学十佳青年科技标兵(2007年)
2000年-2005年沈阳药科大学“十五”青年科技新星(2006年)

主要研究方向
1. 不对称合成方法及其在手性药物合成中的应用研究
2. 天然活性产物的结构修饰及其药理活性研究
3. 药物合成工艺研究

科研情况
主持辽宁省自然科学基金、辽宁省教育厅基金等四项课题。作为主要参与人参与国家十一五重大创新药物基金资助项目两项、国家自然科学基金一项、沈阳市手性药物重点实验室建设项目一项,主持并参与企业合作项目多项。申报国际专利1项、国家专利7项。多次参加国际会议并应邀作大会报告(英文)。

发表论文、著作情况
主编著作8本,分别由人民卫生出版社、人民军医出版社、辽宁科技出版社出版(略)。
已发表科研论文50余篇,近期代表论文如下:
1. Xian Jia, Xingshu Li, Lijin Xu, Yueming Li, Qian Shi, Terry T.-L. Au-Yeung, C. W. Yip, Xinsheng Yao, and Albert S. C. Chan. Titanium-Catalyzed Tandem Sulfoxidation-Kinetic Resolution Process: A Convenient Method for Higher Enantioselectivities and Yields of Chiral Sulfoxide. Advanced synthesis &Catalysis. (2004), 346, 723-726. (IF=5.25)
2. Xingshu Li, Xian Jia, Lijin Xu, Stanton H. L. Kok, C. W. Yip, Albert S. C. Chan. Highly Air- and Water-Stable Fluorinated Ferrocenylphosphine-Aminophosphine Ligands and their Applications in Asymmetric Hydrogenations. Advanced Synthesis & Catalysis. (2005) 347(15), 1904-1908. (IF=5.25)
3. Xian Jia, Xinshu Li, Lijin Xu, Qian, Shi, Xinsheng Yao and Albert S.C. Chan. A highly efficient rhodium/monodentate phosphoramidite catalyst and its application in the enantioselective hydrogenation of enamides and -dehydroamino acid derivatives. Journal of Organic Chemistry. (2003), 68(11), 4539-4541. (IF=4.002)
4. Lu Yin, Yourou Zheng, Xian Jia*, Xingshu Li, Albert S.C. Chan. Efficient and promising asymmetric preparation of enantiopure tolvaptan via transfer hydrogenation with robust catalysts. Tetrahedron: Asymmetry, 2010, 21( 19): 2390-2393 ;(IF=2.52)
5. Gui Lu, Xinshu Li, Xian Jia, Wing-lai Chan, Albert S.C. Chan. Enantioselective alkylation of aromatic ketones catalyzed by chiral camphorsulfonamide ligands. Angwandte Chemie International Edition. (2003),42, 5057-5058. (IF=12.73)
6. Lu Yin , Xian Jia *, Xing Shu Li , Albert S.C. Chan. Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air. Chinese Chemical Letters. 2010 (21): 774–777.
7. Lu Yin, Xian Jia, Xingshu Li, Albert S. C. Chan. A rapid and green approach to chiral a-hydroxy esters: asymmetric transfer hydrogenation (ATH) of a-keto esters in water by use of surfactants. Tetrahedron: Asymmetry. 2009,20(17): 2033-2037. (IF=2.52)
8. Lu Yin, Wenjun Shan, Xian Jia, Xingshu Li,, Albert S.C. Chan. Ru-catalyzed enantioselective preparation of methyl (R)-o-chloromandelate and its application in the synthesis of (S)-Clopidogrel. Journal of Organometallic Chemistry. 694 (2009): 2092–2095. (IF=2.68)
9. Juntao Liu , Di Zhou , Xian Jia , Ling Huang, Xingshu Li , Albert S. C. Chan. A convenient synthesis of (R)-salmeterol via Rh-catalyzed asymmetric transfer hydrogenation. Tetrahedron: Asymmetry. (2008) 19 1824–1828. (IF=2.52)
10. Xinshu Li, Gui Lu, Xian Jia, Yinuo Wu and Albert S. C. Chan. Highly Enantioselective Alkynylation of Aldehydes Using a New BINOL/Ti(Oi Pr)4/Chiral Sulfonamide Catalyst System. Chirality. (2007) 19, 638-641. (IF=2.89)
11. Bao Liu, Juntao Liu, Xian Jia, Ling Huang, Xingshu Lia, and Albert S. C. Chan. The synthesis of chiral N-tosylatedaminoimine ligands and their application in enantioselective addition of phenylacetylene to imines. Tetrahedron: Asymmetry. (2007) 18, 1124–1128. (IF=2.52)
12. Juntao Liu, Bao Liu, Xian Jia, Xingshu Li, and Albert S. C. Chan. Asymmetric addition of alkynes to imines in water catalyzed with a recyclable Cu(I)–bis(oxazoline) and stearic acid system. Tetrahedron: Asymmetry. (2007), 18(14), 396-399. (IF=2.52)
13. Xian Jia, Lu Yin, Xuan Zhao, Xingshu Li. The applications of Schiff bases in Ti-catalyzed asymmetric alkynylation of aldehydes. Chinese Chemical Letters.(2007), 18, 275-278.
14. Xian Jia, Xingshu Li, Wing Sze Lam, Stanton H. L. Kok, Lijin Xu, Gui Lu, Chi-Hung Yeung and Albert S. C. Chan. The synthesis of new chiral phosphine–phosphinites, phosphine–phosphoramidite, and phosphine–phosphite ligands and their applications in asymmetric hydrogenation . Tetrahedron: Asymmetry. (2004), 15(14), 2273-2278. (IF=2.52)
15. Xian Jia, Rongwei Guo, Xinshu Li, Xinsheng Yao and Albert S.C. Chan. Highly enantioselective hydrogenation of enamide catalyzed by rhodium-monodentate phosphoramidite complex. Tetrahedron Letters. (2002), 43, 5541-5544. (IF=2.60)
16. Xinshu Li, Xian Jia, Gui Lu, Terry T.-L. Au-yeung, Kim-Hung Lam, Thomas W. H. Lo and Albert S.C. Chan. Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidites derived from H8-BINOL. Tetrahedron Asymmetry. (2003), 14(18). 2687-2691. (IF=2.52)
17. Xinshu Li, Xian Jia and Albert S.C. Chan. The preparation of fluorinated ferrocenyl phosphine-phosphite, aminophosphine-phosphine ligands. Abstract of Papers, 226th ACS national meeting, New York, NY. United States, September 7-11, 2003, Catl-024.

关注新东方在线服务号

回复【考博真题】领取备考必看真题集

更多资料
更多>>
更多内容
更多>>
更多好课>>
更多>>
更多资料