浙江大学医学院博士研究生导师简介：盛建中

　　在研基金：

　　1. 国家重点基础研究发展计划(973计划)：辅助生殖诱发胚胎源性疾病的风险评估和机制研究(2012CB944900)，子课题辅助生殖诱发胚胎源性疾病的发生机制研究(2012CB944903)120万，2012.1-2016.12。

　　2. 国家重大科学研究计划(973计划)：雌性生育力维持调节机制研究及生殖资源库建立(2011CB944500)，子课题研究卵母细胞中水通道在卵母细胞冰冻保存中的作用(2011CB944502)250万，2011.1-2015.12。

　　3. 国家自然科学基金: ORP150 和Hsp60 在先兆子痫子代高血压发生中的作用机制。No.81270708，70万，2013.1-2016.12。

　　4. 国家自然科学基金: 血管内皮细胞FSH受体介导的更年期血管功能紊乱的分子机制研究。No.81070268，32万，2011.1-2013.12。

　　5. 浙江省自然科学基金: No.Y2100452, 10万，2010.10-2013.9。

　　6. 教育部博士点基金：6万，2011-2013

　　7. 浙江省卫生厅生殖医学研究团队建设基金：50万，2010-2014。

　　2009年后发表的部分SCI论文(*通讯作者或共同通讯作者)

　　1. Tan YJ, Xiong Y, Ding GL, Zhang D, Meng Y, Huang HF*, Sheng JZ*. Cryoprotectants upregulate the expression of mouse 2 oocyte AQP7 that facilitates water diffusion during cryopreservation. Fertility & Sterility 2012 accepted (IF：3.775)

　　2. Liu XM, Ding GL, Jiang Y, Pan HJ, Zhang D, Wang TT, Zhang RJ, Shu J, Sheng JZ*, Huang HF*. Down-Regulation of S100A11, a Calcium-Binding Protein, in Human Endometrium May Cause Reproductive Failure. J Clin Endocrinol Metab. 2012 2012 Oct;97(10):3672-83. (IF：5.967)

　　3. Ding GL, Wang FF, Shu J, Tian S, Jiang Y, Zhang D, Wang N, Luo Q, Zhang Y, Jin F, Leung PCK, Sheng JZ*, Huang HF*: Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia, Diabetes. 2012 May;61(5):1133-42. (IF：8.286)

　　4. Zhang D, Tan YJ, Qu F, Sheng JZ, Huang HF. Functions of water channels in male and female reproductive systems. Mol Aspects Med. 2012 Oct;33(5-6):676-90. (IF：9.970)

　　5. Zhang RJ, Zou LB, Zhang D, Tan YJ, Wang TT, Liu AX, Qu F, Meng Y, Ding GL, Lu YC, Lv PP, Sheng JZ*, Huang HF*. Functional expression of large-conductance calcium-activated potassium channels in human endometrium: a novel mechanism involved in endometrial receptivity and embryo implantation. J Clin Endocrinol Metab. 2012 Feb;97(2):543-53. (IF=5.967)

　　6. Qu F, Wang FF, Yin R, Ding GL, El-Prince M, Gao Q, Shi BW, Pan HH, Huang YT, Jin M, Peter CK Leung, Sheng JZ, Huang HF*: A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells. J Mol Med (Berl) 2012 Aug; 90(8):911-23.(IF：4.668 )

　　7. Lu YC, Ding GL, Yang J, Zhang YL, Shi S, Zhang RJ, Zhang D, Pan JX, Sheng JZ, Huang HF: Small-conductance calcium-activated K+ channels 3 (SK3) regulate blastocyst hatching by control of intracellular calcium concentration. Hum Reprod 2012, 27:1421-1430(IF：4.475 )

　　8. Zhou LB, Zhang RJ, Tan YJ, Ding GL, Shi S, Zhang D, Liu AX, Wang TT, Leung PCK, Sheng JZ*, Huang HF*. Identification of estrogen response element in the aquaporin-2 gene that mediates estrogen-induced cell migration and invasion in human endometrial carcinoma. J Clin Endocrinol Metab.2011 Sep;96(9):E1399-408.(IF=5.967)

　　9. Raqeeb A， Sheng JZ，Ao N, Braun A. Purinergic P2Y2 Receptors Mediate Rapid Ca2+ Mobilization, Membrane Hyperpolarization and Nitric Oxide Production in Human Vascular Endothelial Cells. Cell Calcium 2011 Apr;49(4):240-8. (SCI收录，IF=4.288).

　　10. Liu AX, He WH, Yin LJ, Lv PP, Zhang Y, Sheng JZ, Leung PCK, Huang HF. Sustained endoplasmic reticulum stress as a cofactor of oxidative stress in decidual cells from patients with early pregnancy loss. J Clin Endocrinol Metab.2011 Mar;96(3):E493-7. (IF=5.967)

　　11. Wang TT, Wu YT, Dong MY, Sheng JZ, Leung PCK, Huang HF. G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve. Fertil Steril. 2010 Nov;94(6):2490-2.(IF=3.970)

　　12. Qu F, Wang FF, Lu XE, Dong MY, Sheng JZ, Lv PP, Ding GL, Shi BW, Zhang D, Huang HF. Altered aquaporin expression in women with polycystic ovary syndrome: hyperandrogenism in follicular fluid inhibits aquaporin-9 in granulosa cells through the phosphatidylinositol 3-kinase pathway. Hum Reprod. 2010, 25(6):1441-450.(IF=3.859)

　　13. Yang Y, Wu X, Gui P, Wu J, Sheng JZ, Ling S, Braun AP, Davis GE, Davis MJ. Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation. J Biol Chem. 2010 Jan 1;285(1):131-41.(IF=5.520)

　　14. Sheng JZ, Ella S, Hill M, Davis M, Braun A. Openers of KCa and IKCa Channels Enhance Agonist-evoked Endothelial Nitric Oxide Synthesis and Arteriolar Vasodilation. FASEB J. 2009 Apr;23(4):1138-45 (IF=7.049)

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