浙江大学医学院博士研究生导师简介：王建莉

　　主要论文：

　　1. Cai Z, Zhang W, Li M, Yue Y, Yang F, Yu L, Cao X, Wang J. TGF-beta1 gene-modified, immature dendritic cells delay the development of inflammatory bowel disease by inducing CD4(+)Foxp3(+) regulatory T cells. Cell Mol Immunol. 2010 Jan;7(1):35-43.

　　2. Rui Y, Liu X, Li N, Jiang Y, Chen G, Cao X, Wang J. . PECAM-1 Ligation Negatively Regulates TLR4 Signaling in Macrophages.J Immunol. 2007 Dec 1;179(11):7344-51. (通讯作者)

　　3. Yang Y, Xiu F, Cai Z, Wang J, Wang Q, Fu Y, Cao X. Increased induction of antitumor response by exosomes derived from interleukin-2 gene-modified tumor cells. J Cancer Res Clin Oncol. 2007 Jun;133(6):389-99.

　　4. Xiu F, Cai Z, Yang Y, Wang X, Wang J, Cao X. Surface anchorage of superantigen SEA promotes induction of specific antitumor immune response by tumor-derived exosomes. J Mol Med. 2007 May;85(5):511-21 (共同通讯作者)

　　5. Yan X, Xiu F, An H, Wang X, Wang J, Cao X. Fever range temperature promotes TLR4 expression and signaling in dendritic cells. Life Sci. 2007 Jan 2;80(4):307-13.

　　6. Zhang Y, Wang X, Xiang Z, Li H, Qiu J, Sun Q, Wan T, Li N, Cao X, Wang J. Promotion of cellular migration and apoptosis resistance by a mouse eye-specific phosphatidylethanolamine-binding protein. Int J Mol Med.2007;19(1):55-63. (通讯作者)

　　7. Wang Q, Li N, Wang X, Shen J, Hong X, Yu H, Zhang Y, Wan T, Zhang L, Wang J, Cao X. Membrane protein hMYADM preferentially expressed in myeloid cells is up-regulated during differentiation of stem cells and myeloid leukemia cells. Life Sci. 2007 Jan 9;80(5):420-9.

　　8. Li D, Yu H, Huang H, Shen F, Wu X, Li J, Wang J, Cao X, Wang Q, Tang G. FGF receptor-mediated gene delivery using ligands coupled to polyethylenimine. J Biomater Appl. 2007 Sep;22(2):163-80.

　　9. Wang J, Cao X, Zhang W, Ye T, Tani K. Treatment of leukemia with fibroblast-mediated interferon-alpha gene therapy alone or in combination with doxorubicin. Leukemia Res, 1996;20(5):379-384

　　10. Wang J, Saffold S, Cao X, Krauss J, Chen W. Eliciting T cell immunity Against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines. The Journal of Immunology. 1998; 161: 5516-5524

　　11. Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. 2001;281(4):878-883. (共同第一作者)

　　12. He X, Wang J, Guo Z, Liu Q, Chen T, Wang X, Cao X. Requirement for ERK activation in sinomenine-induced apoptosis of macrophages. Immunol Lett. 2005, 98(1): 91-96 (共同第一作者)

　　13. Sun W, He X, Guo Z, Wang Q, Li X, Rayner J, Zhang L, Wang J, Cao X. IL-12p40-overexpressing immature dendritic cells induce T cell hyporesponsiveness in vitro but accelerate allograft rejection in vivo: Role of NK cell activation and interferon-gamma production. Immunol Lett. 2004, 94:191-199 (共同通讯作者).

　　14. Chen W, Wang J, Shao C, Liu S, Yu Y, Wang Q, Cao X. Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells. Eur J Immunol. 2006 ;36(6):1598-607.

　　15. Wang Q，Liu Y，Wang J，Ding G，ZhangW，Chen G，Zhang M，Zheng S, Cao X. Induction of Allospecific Tolerance by Immature Dendritic Cells Genetically Modified to Express Soluble TNF Receptor. The Journal of Immunology. 2006;177(4):2175-85. (Q.W and Y.L. contributed equally to this study)

　　16. Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochem Biophys Res Commun. 2006 ; 345(3):1122-30.

　　17. Tang H, Guo Z, Zhang M, Wang J, Chen G, Cao X. Endothelial stroma programs hematopoietic stem cells to differentiate into regulatory dendritic cells through IL- 10. Blood. 2006;108(4) :1189-97.

　　18. Chen W, Wang J, An H, Zhou J, Zhang L, Cao X. Heat shock up-regulates TLR9 expression in human B cells through activation of ERK and NF-κB signal pathways. Immunol Lett. 2005, 98(1): 153-159.

　　19. Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8(+) CTL response. J Cancer Res Clin Oncol. 2005 ;131(7):468-78.

　　20. Sun H, Li N, Wang X, Chen T, Shi L, Zhang L, Wang J, Wan T, Cao X. Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells. Mol Cell Biochem. 2005; 269(1-2):85-94

　　21. Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Liu Y, Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004, 94(1-2): 141-151.

　　22. Zhang M, Tang H, Guo Z, An H, Zhu X, Song W, Guo J, Huang X, Chen T, Wang J, Cao X. Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells, Nature Immunology. 2004, 5(11):1124-1133.

　　23. Chen T, Guo J, Yang M, Han C, Zhang M, Chen W, Liu Q, Wang J, Cao X. Cyclosporin A impairs dendritic cell migration by regulating chemokine receptor expression and inhibiting cyclooxygenase-2 expression. Blood. 2004; 103(2)： 413-421.