浙江大学医学院博士研究生导师简介：金洪传

　　代表性论文：

　　第一和通讯作者论文

　　Pre-2009

　　1. Jin H., Sperka T., Herrlich P. and Morrison H. Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase. Nature 2006;442(7102):576-9 (IF：36.1)

　　2. Jin H.*, Wang X.*, Ying J., Wong AH, Li H, Lee KY, Chan AT, Yeo W, Ma BB, Lung ML, Shen ZY, Xu LY, Langford C and Tao Q. Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in multiple carcinomas. Oncogene. 2007;26(53):7490-7498 (IF：7.2)

　　3. Jin H., Wang X, Ying J, Wong AH, Cui Y, Shen ZY, Li EM, Zhang Q, Jin J, Kupzig S, Chan AT, Cullen PJ and Tao Q. Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in cancers. Proceedings of the National Academy of Sciences 2007;104(30):12353-8 (IF：9.8)

　　4. Cheng YY*, Jin H*, Liu X, Siu JM, Wong YP, Ng EK, Yu J, Leung WK, Sung JJ and Chan FK. Fibulin 1 (FBLN1) is downregulated through promoter hypermethylation in gastric cancer. British J. of Cancer. 2008;99(12):2083-2087 *: 共同第一作者 (IF：4.9)

　　2009

　　5. Liu X, Lam EK, Wang X, Zhang JB, Cheng YY, Lam YW, Ng EKO, Yu J, Chan FKL, Jin HC* and Sung JJY. Promoter hypermethylation mediates downregulation of thiamine receptor SLC19A3 in gastric cancer. Tumor Biology 2009;242-248 *:通讯作者 (IF：2.0)

　　6. Wang X, Lam EK, Zhang JB, Jin HC*, Sung JJ. MicroRNA-122a functions as a novel tumor suppressor downstream of adenomatous polyposis coli in gastrointestinal cancers Biochem Bioph Res Com 2009; 387(2):376-380 *:通讯作者 (IF：2.6)

　　7. Wang LJ, Jin HC*, Wang X, Lam EK, Zhang JB, Liu X, Chan FK, Si JM, Sung JJ*. ZIC1 is downregulated through promoter hypermethylation in gastric cancer. Biochem Bioph Res Com 2009;379(4):959-63 *:通讯作者 (IF：2.6)

　　2010

　　8. Wang X and Jin H*. The epigenetic basis of Warburg effect Epigenetics 2010;5(7):566-568 *:通讯作者 (IF：4.7)

　　9. Liu X, Wang X, Zhang JB, Lam EK, Shin VY, Cheng YY, Cheng AS, Yu J, Chan FK, Sung JJ and Jin HC*. Warburg effect revisited: an epigenetic link between aerobic glycolysis and gastric carcinogenesis Oncogene 2010;29:442-450 *:通讯作者 (IF：7.2)

　　2011

　　10. Han W, Sun J, Feng L, Wang K, Li D, Pan Q, Chen Y, Jin W, Wang X, Pan H* and Jin H*. Autophagy Inhibition Enhances Daunorubicin-induced Apoptosis in K562 cells PLoS One 2011;e028491 *: 通讯作者 (IF：4.8)

　　11. Feng LF, Wang X* and Jin HC*. Rabbit monoclonal antibody: potential application in cancer therapy American Journal of Translational Research 2011;3(3):269-274 *: 通讯作者

　　12. Han W, Pan H*, Chen Y, Sun J, Wang Y, Li J, Ge W, Feng L, Lin X, Wang XJ, Wang X, Jin H*. EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells PLoS One 2011;6(6):e18691 *:通讯作者 (IF：4.8)

　　13. Lam EK, Wang X*, Shin V, Zhang S, Morrison H, Sun J, Ng EK, Yu J and Jin H*. A microRNA contribution to aberrant Ras activation in gastric cancer. American Journal of Translational Research 2011;3(2):209-218 *:通讯作者

　　14. Wang L, Wang X*, Wang XJ, Pan J, Lu HQ, Zhang SJ, Lin XY, Lam EK, Cui Y, Yu J and Jin HC*. Klotho is silenced through promoter hypermethylation in gastric cancer American Journal of Cancer Research 2011;1(1):111-119 *:通讯作者

　　2012

　　15. Zhang S, Jiang T, Feng L, Sun J, Lu H, Wang Q, Pan M, Huang D, Wang X, Wang L* and Jin H*. Yin Yang-1 suppresses differentiation of hepatocellular carcinoma cells through the downregulation of CCAAT/enhancer-binding protein alpha Journal of Molecular Medicine 2012 Sep;90(9):1069-77 *: 通讯作者 (IF：5.2)

　　16. Wang L, Chen S, Xue M, Zhong J, Wang X, Gan L, Lam E, Liu X, Zhang J, Zhou T, Yu J, Jin H* and Si J*. Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis Molecular Medicine 2012 May 9;18(1):389-400 *: 通讯作者 (IF：5.9)

　　17. Feng L, Pan M, Sun J, Lu H, Shen Q, Zhang S, Jiang T, Liu L, Jin W, Chen Y, Wang X*, Jin H*. Downregulation of p53 Up-regulated Modulator of Apoptosis by histone deacetylase 3 in gastric cancer Journal of Molecular Medicine 2012 Accepted *: 通讯作者 (IF: 5.2)

　　其他论文

　　Pre-2009

　　18. Ma W, Yu H, Wang Q, Bao J, Yan J, Jin H. In vitro biological activities of transmembrane superantigen staphylococcal enterotoxin A fusion protein. Cancer Immunol Immunother. 2004;53(2):118-24 (IF：4.3)

　　19. Ma W., Yu H., Wang Q., Jin H., and Labhasetwar V. A Novel approach for Cancer Immunotherapy: Tumor Cells Anchored with SEA Generate Effective Antitumor Immunity. Journal of Clinical Immunology 2004;24(2):294-301 (IF：3.3)

　　20. Chan L., Cui Y., Hasselt A., Li, HY, Srivastava G., Jin H., Ng M, Wang Y, Lee KY, Tsao GS, Zhong S, Chan AT and Tao Q. The tumor suppressor Wnt inhibitory factor 1 (WIF1) is frequently methylated in nasopharyngeal and esophageal carcinomas Laboratory Investigation 2007; 87(7):644-50 (IF：4.4)

　　21. Shin VY, Jin HC, Ng EK, Yu J, Leung WK, Cho CH and Sung JJ. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. Toxicol Appl Pharmacol. 2008; 233(2):254-261 (IF：3.9)

　　22. Yu J, Tao Q, Cheung K, Jin H, Poon FF, Wang X, Li H, Cheng YY, Roechen C, Ebert MP, Chan AT and Sung JJ. Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors Hepatology 2008;48(2):508-518 (IF：10.9)