武汉大学生命科学学院博士生导师简介：宋质银

　　代表性论文:

　　1. Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z*. (2015) Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death and Differentiation. doi: 10.1038/cdd.2015.102. [Epub ahead of print]

　　2. Zhang K, Li H, Song Z*. (2014) Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage. EMBO Reports, 15(5):576-85

　　3. Ruan Y, Li H, Zhang K, Jian F, Tang J, Song Z*. (2013) Loss of Yme1L Perturbates Mitochondrial Dynamics. Cell Death & Disease, 4:e896

　　4. Losón OC, Song Z, Chen H, Chan DC. (2013) Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Molecular Biology of the Cell. 24(5):659-67

　　5. Gautier CA, Giaime E, Caballero E, Núñez L, Song Z, Chan DC, Villalobos C, Shen J. (2012) Regulationof mitochondrial permeability transition pore by PINK1. Molecular Neurodegeneration. 7:22

　　6. Miao L#, Song Z #, Jin L, Zhu YM, Wen LP and Wu M. (2010) ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation. Oncogene, 29(5):711-722 (co-first author)

　　7. Ban T, Heymann JA, Song Z, Hinshaw JE, Chan DC. (2010) OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation.Human Molecular Genetics. 19(11):2113-22

　　8. Song Z, Ghochani M, McCaffery JM, Frey TG, Chan DC (2009) Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion. Molecular Biology of Cell. 20(15):3525-32.

　　9. Song Z, Chen H, Fiket M, Alexander C, Chan DC. (2007) OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L. Journal of Cell biology. 178(5):749-755

　　10. Ma L, Huang Y, Song Z, Feng S, Tian X, Du W, Qiu X, Heese K, Wu M. (2006) Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. Cell Death and Differentiation. 13(12): 2079-88.

　　11. Zhu DE, Höti N, Song Z, Jin L, Wu Z, Wu Q, Wu M. (2006) Suppression of tumor growth using a recombinant adenoviral vector carrying the dominant-negative mutant gene Survivin-D53A in a nude mice model. Cancer Gene Therapy. 13(8):762-70

　　12. Song Z, Wu M. (2005) Identification of a novel nucleolar localization signal and a degradation signal in Survivin-deltaEx3: a potential link between nucleolus and protein degradation.Oncogene. 14; 24(16): 2723-2734

　　13. Song Z, Liu S, He H, Hoti N, Wang Y, Feng S, Wu M. (2004) A Single Amino Acid Change (Asp 53->Ala53) Converts Survivin from anti-apoptotic to pro-apoptotic. Molecular Biology of Cell. 15(3):1287-1296

　　14. Song Z, Yao X and Wu M. (2003) Direct interaction between Survivin and Smac is essential for the anti-apoptotic activity of Survivin during Taxol-induced apoptosis. Journal of Biological Chemistry. 278(25): 23130-23140

　　15. Höti N, Zhu DE, Song Z, Wu Z, Tabassum S, Wu M. (2004) p53-dependent apoptotic mechanism of a new designer bimetallic compound Tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): In vivo studies in Wistar rats as well as in vitro studies in human cervical cancer cells. Journal of Pharmacology and Experimental Therapeutics. 311(1):22-33

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