武汉大学药学院博士生导师简介：肖玉秀

　　5. 主持武汉大学研究生精品课程建设项目《药物代谢与体内药物分析》，2015-2016

　　近年发表的代表性论文：

　　1. Yu Tian, Ran Wei#, Bo Cai, Jinfeng Dong, Bin Deng, Yuxiu Xiao*. Cationic gemini pyrrolidinium surfactants based sweeping-micellar electrokinetic chromatography for simultaneous detection of nine organic pollutants in environmental water. Journal of Chromatography A, 1475 (2016, December) 95–101.

　　2. Cao Li, Jia Xu#, Dan Chen, Yuxiu Xiao*. Detection of phthalates migration from disposable tablewares to drinking water using hexafluoroisopropanol-induced catanionic surfactant coacervate extraction. Journal of Pharmaceutical Analysis, 6 (2016, October): 292-299.

　　3. Jia Xu, Manli Niu, Yuxiu Xiao*. Hexafluoroisopropanol-induced catanionic surfactants based coacervate extraction for analysis of lysozyme. Anal Bioanal Chem, 2016, doi:10.1007/s00216-016-0054-3.

　　4. Yunfang Li, Jia Xu, Yu Chen, Zhinan Mei, Yuxiu Xiao*. Screening of inhibitors of glycogen synthase kinase-3β from traditional Chinese medicines using enzyme-immobilized magneticbeads combined with high-performance liquid chromatography. Journal of Chromatography A, 1425 (2015, December) 8–16.

　　5. Yu Tian, Yunfang Li, Jie Mei, Bo Cai, Jinfeng Dong, Zhiguo Shi, Yuxiu Xiao*. Simultaneous separation of acidic and basic proteins using geminipyrrolidinium surfactants and hexafluoroisopropanol as dynamic coating additives in capillary electrophoresis. Journal of Chromatography A, 1412 (2015, September) 151–158.

　　6. Yu Tian, Yunfang Li, Jie Mei, Bin Deng, Yuxiu Xiao*. Hexafluoroisopropanol-modified cetyltrimethylammoniumbromide/sodium dodecyl sulfate vesicles as a pseudostationary phase in electrokinetic chromatography. Journal of Chromatography A, 1404 (2015, July) 131–140.

　　7. Yao Xiao, Yunfang Li, Jinjin Ying, Yu Tian, Yuxiu Xiao*, Zhinan Mei**. Determination of alditols by capillary electrophoresis with indirect laser-induced fluorescence detection. Food Chemistry 2015 174: 233–239.

　　8. Bin Deng, Yu Tian, Xu Yu, Jian Song, Feng Guo, Yuxiu Xiao*, Zhiling Zhang**. Laminar flow mediated continuous single-cell analysis on a novel poly(dimethylsiloxane) microfluidic chip. Analytica Chimica Acta, 2014, 820: 104-111.

　　9. Yunfang Li, Yu Chen, Chuying Xiao, Dan Chen, Yuxiu Xiao*, Zhinan Mei**. Rapid screening and identification of alpha-amylase inhibitors fromGarcinia xanthochymus using enzyme-immobilized magneticnanoparticles coupled with HPLC and MS. Journal of Chromatography B, 2014, 960 166–173.

　　10. Bin Deng, Zhi-Ming Wang, Zi-Hao Zhou, Yi-Meng Liu, Jian Song, Yu-Xiu Xiao*. Quantitative study of cellular heterogeneity in doxorubicin uptake and its pharmacological effect on cancer cells. Biomedical Chemistry 2014, 2014, 28: 1393–1401.

　　11. Dan Chen, Pei Zhang, Yunfang Li, Zhinan Mei, Yuxiu Xiao*. Hexafluoroisopropanol-induced coacervation in aqueous mixed systems of cationic and anionic surfactants for the extraction of sulfonamides in water samples. Anal Bioanal Chem 2014, 406(24) : 6051-6060.

　　12. Bin Deng, Yuxiu Xiao*. Heterogeneous cellular drug uptake in chemotherapy. Cancer Cell & Microenvironment 2014, 1: e272.

　　13. Han-Peng Jiang, Jiu-Xia Zhu, Chunyan Peng, Jiajia Gao, Fang Zheng, Yu-Xiu Xiao, Yu-Qi Feng* and Bi-Feng Yuan*. Facile one-pot synthesis of a aptamer-based organic–silica hybrid monolithic capillary column by “thiol–ene” click chemistry for detection of enantiomers of chemotherapeutic anthracyclines. Analyst, 2014,139: 4940-4946.

　　14. Bin Deng, Zhiming Wang, Jian Song, Yuxiu Xiao*, Dan Chen, Jun Huang. Analysis of doxorubicin uptake in single human leukemia K562 cells using capillary electrophoresis coupled with laser-induced fluorescence detection. Anal Bioanal Chem 2011, 401: 2143–2152.

　　15. Zhi-Guo Shi*, Qing-Zhong Guo, Yi-Ting Liu, Yu-Xiu Xiao*, Li Xu. Drug delivery devices based on macroporous silica spheres. Materials Chemistry and Physics 2011, 126: 826–831 (co-corresponding author).

　　16. Jie Mei, Yan-Ping Tian, Wen He, Yu-Xiu Xiao*, Juan Wei, Yu-Qi Feng. Preparation approaches of the coated capillaries with liposomes in capillary electrophoresis. J Chromatogr A 2010, 44: 6979-6986.

　　17. Deng Bin, Xu Jianrong, Wang Zhiming, Xiao Yuxiu*. Single-cell analysis using capillary electrophoresis. Progress in Chemistry, 2010, 22(11): 2215-2223.

　　专 利：

　　1. 肖玉秀，邓彬. 一种两用激光诱导荧光检测系统. 专利号：ZL 201310012461.6, 证书号：第1650205号，授权公告日：2015年4月29日

　　2. 肖玉秀，吴喆，梅洁. 一种混合表面活性剂双水相萃取体系. 专利号 201110287840.7，授权公告日：2014年4月15日

　　3. 肖玉秀, 徐见容. 一种用于正交式激光诱导荧光检测器的四维可调毛细管夹持器. 专利号 ZL 200820230546.6, 授权公告日2009年10月9日

　　4. 肖玉秀，徐见容，倪峙旭. 一种毛细管窗口制作器. 专利号 ZL 200920084847.7，授权公告日2010年5月12日

　　5. 肖玉秀，汪志明，徐见容，倪峙旭. 一种毛细管冲洗及进样两用器. 专利号 ZL 200920228727.X，授权公告日2010年6月9日

　　6. 肖玉秀，廖晓燕，蒋永光. 奥沙普秦固体分散体、制备方法及应用. 申请号 201110202153.0，申请日期：2011年7月19日

　　招聘信息：

　　诚邀博士后加盟本课题组。欢迎校内外优秀学生报考本课题组博士生、硕士生。