浙江大学医学院博士研究生导师简介：项春生

　　Kanbe, K., K. Inoue, C. Xiang and Q. Chen. 2006. Identification of clock as a mechanosensitive gene by large-scale DNA microarray analysis: downregulation in osteoarthritic cartilage. Modern Rheumatology, 16(3): 131-136.

　　Hansson, S.R., Y. Chen, J. Brodszki, M. Chen, E. Hernandez-Andrade, J.M. Inman, O.A. Kozhich, I. Larsson, K. Marsal, P. Medstrand, C.C. Xiang and M.J. Brownstein. 2006. Expression profiling of human placentas from preeclamptic and nonmotensive pregnancies. Molecular Human Reproduction, 12(3): 169-179.

　　Inoue, Y., A.M. Yu, S.H. Yim, X. Ma, K.W. Krausz, J. Inoue, C.C. Xiang, M.J. Brownstein, G. Eggertsen, I. Bjorkhem and F.J. Gonzalez. 2006. Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha. Journal of Lipid Research, 47(1): 215-227.

　　Mutuga-Nakayama, N., T. Shahar, J.G. Verbalis, M.J. Brownstein, C. Xiang and H. Gainer. 2005. Regulation of gene expression in Magnocellular Neurons in Rat Supraoptic Nucleus during Sustained Hypoosmolality. Endocrinology, 146(3): 1254-1267.

　　Arraztoa, J.A., J. Zhou, D. Marcu, C. Cheng, R. Bonner, M. Chen, C. Xiang, M. Brownstein, K. Maisey, M. Imarai and C. Bondy. 2005. Identification of Genes expressed in primate primordial oocytes. Human Reproduction, 20(2): 476-483.

　　Xiang, C., E. Mezey, M. Chen, S. Key, L. Ma and M. Brownstein. 2004. Using DSP, a Reversible Crosslinker, to Fix Tissues for Immunostaining, Microdissection, and Expression Profiling. Nucleic Acids Research, 32 (22): e185.

　　Mutuga-Nakayama, N., T. Shahar, J.G. Verbalis, M.J. Brownstein, C. Xiang, R.T. Bonner and H. Gainer. 2004. Selective gene expression in Magnocellular Neurons in Rat Supraoptic Nucleus. Journal of Neuroscience, 24(32): 7174-7185.

　　Xiang, C*., M. Chen, L. Ma, Q. Phan, J. Inman, O. Kozhich and M. Brownstein. 2003. A new strategy to amplify degraded RNA from small tissue samples for microarray studies. Nucleic Acids Research, 31 (9): e53.

　　Xiang, C., M. Chen, O. Kozhich, Q. Phan, J. Inman, Y. Chen and M. Brownstein. 2003. Probe generation directly from small numbers of cells for DNA microarray studies. BioTechniques. 34: 386-393.

　　Xiang, C. and M. Brownstein. 2003. Fabrication of cDNA microarrays. In: Methods in Molecular Biology: vol. 224: Functional Genomics: Methods and Protocols. Edited by: M.J. Brownstein and A. Khodursky. Humana Press Inc., Totowa, NJ. pp. 1-7.

　　Xiang, C. and M. Brownstein. 2003. Preparing fluorescent probes for microarray studies. In: Methods in Molecular Biology: vol. 224: Functional Genomics: Methods and Protocols. Edited by: M.J. Brownstein and A. Khodursky. Humana Press Inc., Totowa, NJ. pp. 55-60.

　　Xiang, C., O. Kozhich, M. Chen, J. Inman, Q. Phan, Y. Chen and M. Brownstein. 2002. Amine-modified random primers to label probes for DNA microarray. Nature Biotechnology, 20(7): 738-742.

　　Paulose-Murphy, M., K. Ha, C. Xiang, Y. Chen, M. Bittner, L. Gillim, C. Gooden, S. Leighton, P. Meltzer, F. Newcomb, J. Black, T. Pohida, P. Smith, J. Trent, R. Yarchoan and S. Zeichner. 2001. The transcription program of the human Herpesvirus-8 (Kaposi’s sarcoma associated herpesvirus). Journal of Virology, 75 (10): 4843-4853.

　　Xiang, C*. and Y. Chen. 2000. cDNA microarray technology and its applications. Biotechnology Advances, 18 (2000): 35-46.

　　主要科研项目：

　　1)Brain molecular anatomy project

　　美国NIH研究项目(共同主持人)75万美元，2000-2003

　　2)New technology development for functional genomics studies

　　美国NIH研究项目(主持人)100万美元, 2001-2005

　　3)Development of diagnostic chips for rapid detection of Category A List pathogens

　　美国NIH/FDA生物防御专项(主持人)50万美元, 2002-2005

　　4)Nanoparticle based BCA assay for sensitive detection of category A and B pathogens

　　美国NIH/FDA生物防御专项(共同主持人)40万美元, 2005-2009

　　5)Quorom sensing in pathogenic Burkholderia: host responses to bacterial infections

　　美国国防部基金项目(共同主持人)总经费500万美元, 2005-2010

　　6)肠道微生态与感染的基础研究

　　国家973项目(首席科学家和第一子课题负责人)总经费3760万人民币，2007-2011

　　7)乙肝(肝癌)新型免疫疗法及药物靶位点的研究

　　十一五传染病重大专项(子课题负责人)100万人民币，2008-2011

　　8)传染病检测技术研究-传染病病原体诊断和组合检测技术

　　十一五传染病重大专项(子课题负责人)200万人民币，2008-2011

　　9)抗乙肝病毒的新靶标研究

　　国家“十二五”重大专项(课题负责人)待拨， 2011-2013

　　10)干细胞移植治疗心力衰竭

　　国家863项目(子课题负责人)待拨，2011-2014

　　11)细胞移植与治疗关键技术及产品研发

　　国家863项目(十二五)(子课题负责人)待拨，2012-2015

　　12)干细胞临床应用技术研发创新团队

　　浙江省科技厅科技创新项目(课题负责人)待拨，2011-2014